Apropos of the ask on paralytic toxins, are there any substances that could be used as a nonlethal “paralytic” against a healthy human target? That, perhaps, interfere with coordination enough to immobilize a person but without stopping crucial body functions? Or does that just bring is back to typical tranquilizers? And, you’ve probably answered this before, but how fast do those work?
Well, you can get them drunk. Alcohol and most mild sedatives can impair someone without actually putting them under. There is an element of risk, but it’s not particularly pronounced. (Unless you’re combining them, in which case things can turn really nasty, fast.) Usually the hard part is when someone wants to actually put someone under, or when they want to administer this stuff covertly via a dart.
Most tranquilizers take about 30 minutes to kick in (with a pretty massive margin for error based on the subject’s metabolism.) Again, this isn’t much of a problem when you’re dealing with a bear wandering around the subdivision, but doesn’t really lend itself to someone sneaking around.
General anesthesia is an exception to this. In that case you’re looking at an onset of under a minute. But, as we’ve discussed before, the problem with anesthesia is, you need someone there monitoring the subject’s vitals to adjust the dosage and keep them alive.